Description: Megestrol Acetate is a synthetic progestin, a type of female hormone. It is a derivative of progesterone.

Indication: It is used to treat loss of appetite (anorexia), wasting (cachexia), and significant unexplained weight loss in patients with AIDS. It is also used to treat advanced breast cancer and endometrial cancer.

Mechanism of Action: The exact mechanism for its effect on appetite and weight gain is not fully understood, but it is believed to be related to its effects on appetite-regulating hormones. In cancer treatment, it works by inhibiting the growth of hormone-sensitive tumors by modifying the effects of estrogen on the body.