Description: Bupivacaine is a potent, long-acting local anesthetic that belongs to the amide class of anesthetics. It is typically administered via injection to numb a specific area of the body. It causes a reversible loss of sensation and prevents pain without causing a loss of consciousness.

Indication: Bupivacaine is indicated for the production of local or regional anesthesia or analgesia for a variety of purposes, including:

• Surgical procedures
• Dental and oral surgery
• Diagnostic and therapeutic procedures
• Obstetrical procedures (e.g., labor pain relief)
• Post-operative pain relief

Mechanism of Action: Bupivacaine works by blocking nerve impulses. It does this by reversibly binding to and blocking the voltage-gated sodium channels in the neuronal membrane. This action prevents the influx of sodium ions, which is essential for the initiation and conduction of nerve impulses. By stabilizing the nerve cell membrane it inhibits the transmission of pain signals and other sensations.