Description Laspay (Mebeverine HCl 200mg) is an antispasmodic medication used to treat the symptoms of irritable bowel syndrome (IBS) and other gastrointestinal conditions. Mebeverine works directly on the smooth muscles of the gut to relieve painful spasms and cramps without affecting normal gut motility. It is a well-tolerated and effective treatment for symptoms such as abdominal pain, cramping, bloating, and diarrhea or constipation associated with IBS. Laspay is suitable for long-term use and is typically taken as directed by a healthcare professional.

Indications

• Irritable Bowel Syndrome (IBS)
• Abdominal cramps and pain caused by gastrointestinal spasms
• Spastic colon
• Chronic functional bowel disorders
• Bowel disturbances

Mechanism of Action Mebeverine HCl is a musculotropic antispasmodic agent. It acts directly on the smooth muscle of the gastrointestinal tract, primarily in the colon, to relax it and relieve spasms. Unlike anticholinergic drugs, its action is not mediated through the autonomic nervous system. It directly blocks the voltage-dependent potassium channels (K+) and calcium channels (Ca2+) in the muscle cells, reducing muscle contraction and relieving painful cramps and spasms without inhibiting normal intestinal motility. This makes it effective at treating symptoms without causing significant side effects like dry mouth or blurred vision.