Based on the provided list of categories, “Ometo” falls under the GIT Drugs Segment (Gastrointestinal Tract Drugs Segment).

“Ometo” is a brand name for a drug containing omeprazole. In some cases, it may also be a combination drug, like Ometo-D, which contains both omeprazole and domperidone.

Here is a breakdown of the product’s details:

• Description:
  • Ometo is a medication containing omeprazole, which is a type of proton pump inhibitor (PPI).
  • When the drug also contains domperidone (e.g., Ometo-D), it is a combination medication that includes both a PPI and a prokinetic agent (domperidone).
• Indication:
  • Ometo is primarily used to treat conditions caused by excess stomach acid.
  • Common indications include:
    • Gastroesophageal Reflux Disease (GERD): A chronic condition where stomach acid flows back into the food pipe (esophagus), causing symptoms like heartburn.
    • Peptic Ulcers: Sores that form on the lining of the stomach or small intestine.
    • Zollinger-Ellison Syndrome: A rare condition that causes the stomach to produce too much acid.
    • Healing of erosive esophagitis.
    • In some cases, it is used in combination with antibiotics to treat Helicobacter pylori (H. pylori) infection, which can cause ulcers.
  • The domperidone component in combination products helps to relieve symptoms like nausea, vomiting, and bloating by increasing the movement of the stomach and intestines.
• Mechanism of Action:
  • Omeprazole: It works by irreversibly blocking the H+/K+ ATPase enzyme system, also known as the “proton pump,” in the parietal cells of the stomach. This pump is the final step in the production of gastric acid. By inhibiting this pump, omeprazole effectively reduces both the basal (normal) and stimulated production of stomach acid.
  • Domperidone (if present): It acts as a dopamine antagonist. It works on the upper digestive tract to increase the movement and contractions of the stomach and intestines, helping food move through the digestive system more easily and preventing reflux.